Pennant Research and Development | Walking Guardian-Pennant Biotechnology and Jiangnan University patented Lactobacillus casei
Release time:
2021-03-19
Source:
Recently, the Chinese invention patent of Lactobacillus casei CCFM1074/JN-03 jointly developed by Penn Biosciences and Jiangnan University was approved. Lactobacillus casei CCFM1074/JN-03 can alleviate rheumatoid arthritis and is expected to help improve patients' burden of life due to rheumatoid arthritis. Lactobacillus casei (Lactobacillus casei) cultivation process only needs culture medium and some cultivation conditions to control, the cost is relatively low, compared with expensive biological preparations, it will not bring rheumatoid arthritis (Rheumatoid Arthritis, RA) patients. The economic burden is too great. It can be added to foods, health products or medicines as probiotics.
Market size
In China, the prevalence rate of rheumatoid arthritis has increased from 5.8 million cases in 2015 to 5.9 million cases in 2019, and is expected to continue to increase from 0.7% annually. The 6.0 million cases in 2020 will increase to 6.1 million in 2024. At the same time, the sales revenue of rheumatoid arthritis drugs in China has increased rapidly from 8.4 billion yuan in 2015 to 13.3 billion yuan in 2019, with a compound annual growth rate of 12.3%. It is expected that it will further increase by 22.2% from 2020 to 2024. The compound annual growth rate will increase, reaching 35.2 billion yuan in 2024.
Disease characteristics
Rheumatoid arthritis is a chronic and systemic autoimmune disorder disease characterized by joint synovial inflammation and chronic inflammation of pannus. The common clinical manifestations are joint stiffness, swelling, and pain. As the disease progresses, it will cause joint cartilage and The destruction of bone tissue will eventually lead to joint deformities and impaired mobility. Moreover, there is no cure for rheumatoid arthritis. Once a patient is diagnosed, he often feels that “life is better than death”, so people often say that rheumatoid arthritis is “an undead cancer”. If rheumatoid arthritis is not controlled, as the damage progresses, joint disability will eventually occur, which will seriously affect daily life.
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